Rheumatoid Arthritis Multiple Choice Exam MCQ Questions With Answers

Here are some multiple choice questions and answers related to Rheumatoid Arthritis:

What is the primary cause of Rheumatoid Arthritis?

a. Bacterial infection

b. Genetic predisposition

c. Viral infection

d. Autoimmune disorder

Answer: d. Autoimmune disorder

What joints are commonly affected by Rheumatoid Arthritis?

a. Knees and ankles

b. Fingers and toes

c. Hips and shoulders

d. All of the above

Answer: d. All of the above

What are the common symptoms of Rheumatoid Arthritis?

a. Pain and stiffness in the joints

b. Fatigue and weight loss

c. Warm, red and swollen joints

d. All of the above

Answer: d. All of the above

Which of the following is a treatment option for Rheumatoid Arthritis?

a. Physical therapy

b. Anti-inflammatory drugs

c. Joint injections

d. All of the above

Answer: d. All of the above

Can Rheumatoid Arthritis lead to other health problems?

a. Yes

b. No

Answer: a. Yes

What is the goal of treatment for Rheumatoid Arthritis?

a. To cure the disease

b. To relieve symptoms

c. To slow progression of the disease

d. All of the above

Answer: c. To slow progression of the disease

Can Rheumatoid Arthritis affect other parts of the body besides the joints?

a. Yes

b. No

Answer: a. Yes

What is the role of exercise in managing Rheumatoid Arthritis?

a. Exercise can worsen the symptoms of Rheumatoid Arthritis.

b. Exercise can help improve joint mobility and reduce pain.

c. Exercise is not recommended for individuals with Rheumatoid Arthritis.

Answer: b. Exercise can help improve joint mobility and reduce pain.

Is Rheumatoid Arthritis more common in women or men?

a. Women

b. Men

c. Both equally

Answer: a. Women

Can Rheumatoid Arthritis be prevented?

a. Yes

b. No

Answer: b. No

Here are some scenario-based multiple-choice questions on rheumatoid arthritis:

1) A 55-year-old woman presents to her doctor with complaints of joint pain, swelling, and stiffness that has been affecting her for several months. She reports that the symptoms are worse in the morning and improve throughout the day. On physical examination, her doctor notes swelling and tenderness in her wrist and metacarpophalangeal joints. Which of the following tests would be most helpful in confirming a diagnosis of rheumatoid arthritis?

A. Rheumatoid factor (RF)

B. C-reactive protein (CRP)

C. Antinuclear antibody (ANA)

D. Complete blood count (CBC)

2) A 40-year-old man presents to his doctor with complaints of joint pain, stiffness, and fatigue. He has a history of psoriasis and psoriatic arthritis, which has been well-controlled with medication for the past few years. However, his symptoms have recently worsened, and he is now experiencing pain and swelling in his knees, ankles, and wrists. His doctor suspects that his psoriatic arthritis may have progressed to rheumatoid arthritis. Which of the following symptoms is most characteristic of rheumatoid arthritis?

A. Morning stiffness that lasts for less than 30 minutes

B. Pain that is relieved by rest

C. Joint pain that is symmetric

D. Presence of psoriasis

3) A 65-year-old woman with a long history of rheumatoid arthritis presents to her doctor with complaints of pain and stiffness in her hands, as well as difficulty with fine motor tasks such as buttoning clothes and using utensils. On physical examination, her doctor notes deformities in her fingers, including ulnar deviation, swan neck deformities, and boutonniere deformities. Which of the following treatments is most likely to improve her symptoms?

A. Nonsteroidal anti-inflammatory drugs (NSAIDs)

B. Disease-modifying antirheumatic drugs (DMARDs)

C. Corticosteroids

D. Physical therapy and occupational therapy

4) A 50-year-old man with rheumatoid arthritis presents to his doctor with complaints of persistent joint pain and stiffness despite treatment with disease-modifying antirheumatic drugs (DMARDs) and biologic agents. His doctor suspects that he may be experiencing suboptimal response to these treatments, and decides to switch his biologic agent to a different medication. Which of the following medications is a commonly used biologic agent for rheumatoid arthritis that targets tumor necrosis factor (TNF)?

A. Adalimumab

B. Rituximab

C. Abatacept

D. Tocilizumab

5) A 30-year-old woman with a history of rheumatoid arthritis presents to her doctor with complaints of joint pain and stiffness that have been affecting her for several months. She reports that her symptoms have been well-controlled with nonsteroidal anti-inflammatory drugs (NSAIDs) but she is concerned about the long-term use of these medications. Her doctor recommends a disease-modifying antirheumatic drug (DMARD) to slow down the progression of her disease. Which of the following DMARDs is a commonly used medication that inhibits dihydroorotate dehydrogenase and is associated with potential adverse effects such as gastrointestinal upset, liver toxicity, and bone marrow suppression?

A. Methotrexate

B. Leflunomide

C. Hydroxychloroquine

D. Sulfasalazine

Answers

1) A. Rheumatoid factor (RF) - RF is an autoantibody that is present in up to 80% of patients with rheumatoid arthritis. While a positive RF test is not diagnostic of rheumatoid arthritis, it is a helpful indicator when combined with other clinical and laboratory findings.

2) C. Joint pain that is symmetric - Rheumatoid arthritis typically affects multiple joints in a symmetric pattern, meaning that the same joints on both sides of the body are affected. Psoriatic arthritis, on the other hand, often affects fewer joints in an asymmetric pattern.

3) D. Physical therapy and occupational therapy - While NSAIDs and DMARDs can help relieve pain and slow the progression of rheumatoid arthritis, physical therapy and occupational therapy are important components of treatment to maintain function and improve quality of life.

4) A. Adalimumab - Adalimumab is a TNF inhibitor that is commonly used to treat rheumatoid arthritis. Other commonly used TNF inhibitors include etanercept and infliximab.

5) B. Leflunomide - Leflunomide is a DMARD that inhibits dihydroorotate dehydrogenase, an enzyme involved in the synthesis of pyrimidines. It can cause potential adverse effects such as gastrointestinal upset, liver toxicity, and bone marrow suppression. Methotrexate is another commonly used DMARD, while hydroxychloroquine and sulfasalazine are less potent options.

Maria is a 35-year-old woman who presents to her doctor with joint pain and stiffness in her hands that has been bothering her for several weeks. She also reports feeling fatigued and having a low-grade fever. On examination, her doctor notes swollen and tender joints in her hands and wrists. What is the most likely diagnosis?

A. Osteoarthritis

B. Gout

C. Psoriatic arthritis

D. Rheumatoid arthritis

Answer: D. Rheumatoid arthritis

John is a 50-year-old man who has had rheumatoid arthritis for several years. He has been taking methotrexate, a disease-modifying antirheumatic drug (DMARD), for the past year, but his symptoms have not improved. His doctor decides to add a biologic DMARD to his treatment regimen. Which of the following drugs is a biologic DMARD that may be added to John's treatment?

A. Ibuprofen

B. Celecoxib

C. Methotrexate

D. Infliximab

Answer: D. Infliximab

Sarah is a 60-year-old woman who has had rheumatoid arthritis for many years. She has been taking nonsteroidal anti-inflammatory drugs (NSAIDs) to manage her pain, but they are no longer effective. Her doctor suggests trying a corticosteroid. Which of the following is a potential side effect of long-term corticosteroid use?

A. Increased risk of infection

B. Weight gain

C. Hypotension

D. Dry mouth

Answer: B. Weight gain

David is a 45-year-old man who has just been diagnosed with rheumatoid arthritis. He is interested in trying alternative therapies to manage his symptoms. Which of the following alternative therapies has been shown to have some benefit for rheumatoid arthritis?

A. Acupuncture

B. Chiropractic manipulation

C. Homeopathy

D. Fish oil supplements

Answer: D. Fish oil supplements

Julie is a 55-year-old woman who has been on a combination of DMARDs to manage her rheumatoid arthritis. She has been doing well, but her doctor is concerned about the risk of infection associated with her medications. Which of the following is a potential complication of DMARD use?

A. Cardiovascular disease

B. Liver damage

C. Increased risk of infection

D. Kidney failure

Answer: C. Increased risk of infection